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付绍敏     特聘副研究员(硕导)

研究方向:有机化学

联系方式:          Email:fsm09@aliyun.com

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简历

主要教育和工作经历

2018.5-至今 kaiyun开云官方网站,特聘副研究员

2015.6-2017.12   清华大学化学系,博士后;合作导师:刘强教授

2009.9-2015.4 华南理工大学,化学与化工公司,有机化学专业,博士(指导老师:曾伟教授)

2005.9-2009.7 华南农业大学,理公司,应用化学毕业,学士(指导老师:倪春林教授)

主要研究方向

研究兴趣:

1.基于天然产物全合成的串联环化反应研究

2.天然产物全合成

科研项目:

1. 国家自然科学基金面上项目(2024.1-2027.12),项目批准号:22371192,主持

2. 四川省科技厅,面上项目(2023.1-2024.12),项目批准号:2023NSFSC0105主持

3. 开云全站中国有限公司01”创新项目,2021, 主持

4. 开云全站中国有限公司双百B人才项目, 2021,主持

5. 国家自然科学基金青年基金项目(2020.1-2022.12), 项目批准号:21901170, 主持

6. 国家自然基金委-区域创新联合发展基金,项目批准号:U19A2014,参与

7. 开云全站中国有限公司引进人才科研启动经费项目(2019-2021)

8. 中国博士后科学基金,二等(2015-2017)

获得奖励:

1. 开云全站中国有限公司2021年度本科课堂教学质量优秀奖, 2022

2. 开云全站中国有限公司2022届本科优秀毕业论文二等奖,指导教师,2022

3. 四川省特聘专家, 2021

4. 博士后创新研究基金, 华南理工大学, 2012

5. 华南理工大学学术论文奖, 2011 2015

6. 华南理工大学研究生新生一等奖学金,2009

7. 华南农业大学员工二等奖学金, 2009

8. 华南农业大学优秀毕业论文,2009

代表性成果 (获奖成果、专著、论文、专利)

研究兴趣主要围绕基于目标导向的串联环化反应及其在天然产物合成中的应用开展研究。发展了光诱导电子转移(PET)自由基串联环化反应,并将其成功应用于C20氧化贝壳杉烷二萜天然产物sculponin U的全合成;建立了钯催化半片呐醇重排串联芳基化构筑氢醌类天然产物 dysiherbols A-C 的核心骨架;发展了少见的铁催化串联缺电子烯烃 aldol 反应构建倍半萜 rumphellclovane E 的桥环骨架;基于钯催化串联羰基化/螺环内酯化,通过调控底物取代基的差异性首次实现降三萜 phainanoids中两种手性氧杂螺环内酯的立体多样性合成;拓展了铁催化[5+2]环加成在真菌代谢产物 andilesin C 和二萜生物碱的合成应用;发展了反常区域选择性的铁催化γ/δ-烯基烯酮串联环化合成双环环丙醇。累计发表论文 43篇,它引超过 1000 ,其中以第一(共同)或者共同通讯作者发表论文30篇,包括 J. Am. Chem. Soc. 发表 2 篇,Angew. Chem. Int. Ed. 发表 2 Org. Lett. 6Chem. Comm. 1OCF 3JOC 2两篇论文入选ESI高被引论文,2篇论文引用超过200次,最高它引226

43. Wei Cao, Zhen Wang, Yan Hao, Tianli Wang, Shaomin Fu* and Bo Liu*. Total Synthesis of Sculponin U, A C-20 Oxygenated ent-Kaurane Diterpenoid, through Photoinduced Radical Cascade Cyclization. Angew. Chem. Int. Ed., 2023, 52, e202305516.

42. Ying Sun, Jing Feng, Song Qin, Shaomin Fu* and Bo Liu*. Asymmetric Construction of the Core of C6, C7-Epoxy Daphnane Diterpenoid Orthoesters. Org. Lett., 2023, accepted.

41. Ganxing Huang, Zhengsong Huang, and Xianjian Ma, Zhihu Feng, Fengxia Yuan, Song Qin, Shaomin Fu* & Bo Liu *. Asymmetric Total  Syntheses of Sarbracholide and Shizukaol B. Org. Chem. Front., 2023., 10, 3591-3597. 

40. Lizhi Xun, Zhijiang Zhang, Yuqiao Zhou, Song Qin*, Shaomin Fu*, and Bo Liu. Stereo-divergent Construction of [5, 5]-Oxaspirolactone of Phainanoids. J. Org. Chem., 2023, 88, 3987-3991.

39. Guoshen, Shaomin Fu*., Bo Liu*. Oxime Ester-Enabled Anti-Markovnikov Hydrosilylation of Alkenes. Chem. Commun., 2022, 58(87), 12204-12207.

38. Rong Liu, Mengwei Xia, Cichang Ling, Shaomin Fu*, Bo Liu*. Construction of the Tetracyclic Core Structure of Dysiherbols A−C. Org. Lett., 2022, 24(8), 1642-1646. Highlighted by CBG 资讯.

37. Ying Xie, Wei Huang, Song Qin, Shaomin Fu* and Bo Liu *, Catalytic Radical Cascade Cyclization of Alkene-Tethered Enones to Fused Bicyclic Cyclopropanols. Org. Chem. Front., 20218, 6678-6686.

36. Yi Man, Chengying Zhou, Shaomin Fu*, Bo Liu*. Synthetic Study Aiming at Tricyclic Core of 12-epi-JBIR-23/24. Org. Lett., 2021, 23, 3151-3156.

35. Guanggen Liu+, Zhijiang Zhang+, Shaomin Fu*, Bo Liu*. Asymmetric Total Synthesis of Rumphellclovane E. Org. Lett., 2021, 23, 209-295. + These authors contribute equally to this article. Top ten downloaded article in Organic Letters in December 2020. Highlighted by synfacts, Synfacts 2021, 17(03), 248.

34. Shaomin Fu, Bo Liu.* Recent Progress on Synthesis of Limonoids and Limonoid-like Natural Products. Org. Chem. Front., 2020, 7(14), 1903-1947 (review)

33. Guili Zhu, Chengying Zhou, Song Chen, Shaomin Fu*, Bo Liu*. Construction of BCDEF Core of Andilesin C. Org. Lett., 2019, 19, 7809.

32. Mengqin Hu, Wei Cao, Zhen Wang, Yan Hao, Ganxing Huang, Yuqiao Zhou, Song Qin, Shaomin Fu,* and Bo Liu*. Construction of Angularly Fused Tricyclic Compounds via Photo-induced Radical Cascade Cyclization. Chin. J. Chem., 2023, 41, 25022506.

31. Yunzhou Li, Shaomin Fu* and Bo Liu.* Asymmetric Syntheses of ent-Pimarane Diterpenoids. Org. Biomol. Chem., 2023, 21, 44094413.

30. Cichang Ling, Zhengsong Huang, Yuqiao Zhou, Shaomin Fu*, and Bo Liu*. Alternative Construction of the Core of Lindenane Sesquiterpenoid. Chin. J. Chem., 2023, 41, 1931-1936.

29. 夏梦伟,付绍敏*,刘波*。四环素类抗生素药物的发现、发展与合成:源于天然产物,用于人类健康。《中国科学:化学》,2023, 53, 485-502.

28. Shaomin Fu, Bo Liu*. Chiral Pool Guided Syntheses of Polycyclic Natural Products. Chin. J. Chem., 2022, 40(3), 407-418. 

27. Zhengsong Huang, Ganxing Huang, Xiao Wang, Song Qin, Shaomin Fu, Bo Liu*. Angew. Chem. Int. Ed., 2022, 61(29), e202204303.

26. Xiao Wang, Zhuang Wang, Xianjian Ma, Zhengsong Huang, Ke Sun, Xiang Gao, Shaomin Fu, Bo Liu*. Asymmetric Total Synthesis of Shizukaol J, Trichloranoid C and Trishizukaol A. Angew. Chem. Int. Ed., 2022,134(17), e202200258. DOI:10.1002/anie.202200258

25. Ying Sun, Menqin Hu, Shaomin Fu*, Bo Liu*. Org. Biomol. Chem., 2020, 18, 6443 - 6466. (review)

24. Tianzi Yu, Ying Sun, Canhui Tu, Song Chen, Ting Chen, Shaomin Fu and Bo Liu*. Chem. Sci., 2020, 11(27), 7177. 

23. Bo Liu*,  Shaomin Fu, Chengying Zhou. Nat. Prod. Rep., 2020, 37, 1627 - 1660. (review)

22. Song Chen, Ting Chen, Guanggen Liu, Xiao Wang, Guili Zhu, Yongjiang Liu, Shaomin Fu* and Bo Liu*.Org. Biomol. Chem., 2019, 17, 4711.

21. Biao Du, Zhengsong Huang, Xiao Wang, Ting Chen, Ying Sun, Shaomin Fu  and Bo Liu.* Nature. Commun2019, 10, 1892. Highlighted by CBG News

20. Ting Chen, Song Chen, Shaomin Fu *, Song Qin, Bo Liu*. Synlett., 2019, 30, 903.

19. Rong Liu, Mengwei Xia, Yanhui Zhang, Shaomin Fu*, Bo Liu*. Tetrahedron, 2019, 75, 1781-1794. Zhou Weishan Issue.

18. Yongjiang Liu, Yanhui Zhang, Xiao Wang, Shaomin Fu*, Bo Liu*. Synlett, 2018, 29 (15): 1978.

17. Yi Man, Shaomin Fu*, Juan Chen, and Bo Liu*. Org. Biomol. Chem., 2018, 16, 5043-5049.

16. Jing Feng, Tianzi Yu, Zhijiang Zhang, Jinpeng Li, Shaomin Fu, Juan Chen, and Bo Liu *. Chem. Comm., 2018, 54, 7665-7668. ● Highlighted by X-MOL

15. Jing Feng, Hongli Yin, Yi Man, Shaomin Fu* and Bo Liu*. Chin. J. Chem. 2018, 36, 831-836. ● Selected as back cover paper.

14. Yongjiang Liu, Xiao Wang, Song Chen, Shaomin Fu and Bo Liu*. Org. Lett., 2018, 20 (10), 2934-2938.

Prior to Sichuan University

13. Shaomin Fu, Zhihui Shao, Yujie Wang, Qiang Liu*. J. Am. Chem. Soc., 2017, 139, 11941-11948. († Co-first Author.). Hightlighted by X-MOL. Highly Cited Paper (226 times).

12. Shaomin Fu, Nan-Yu Chen, Xufang Liu, Zhihui Shao, Shu-Ping Luo, and Qiang Liu*. J. Am. Chem. Soc., 2016, 138, 8588-8594. († Co-first Author.). Highly Cited Paper (206 times).

11. Zhihui Shao, † Shaomin Fu, † Mufeng Wei, Shaolin Zhou, Qiang Liu*. Angew. Chem. Int. Ed., 2016, 55, 14653- 14657. († Co-first Author.). Highlighted by Chin. J. Org. Chem. 2017, 37, 242-244. (134 times)

10. Shaomin Fu, Honghao Yang, Guoqiang Li, Yuanfu Deng, Huanfeng Jiang and Wei Zeng *. Org. Lett., 2015, 17(4), 1018- 1021.

9. Shaomin Fu, Huanfeng Jiang, Yuanfu Deng, and Wei Zeng *. Adv. Synth. Catal. 2011, 353, 2795- 2804.

8. Shaomin Fu, Xiaoyan Lian, Tongmei Ma, Wenhua Chen, Meifang Zheng, Wei Zeng*. Tetrahedron. Lett., 2010, 51, 5834- 5837.

7. Libo Liang, Shaomin Fu, Dongen Lin, Xiao-Qi Zhang, Yuanfu Deng, Huanfeng Jiang and Wei Zeng*. J. Org. Chem., 2014, 79, 9472- 9480. († Co-first author.)

6. Wei Zhang, Jun Wei, Shaomin Fu, Dong´en Lin, Huanfeng Jiang, Wei Zeng*. Org. Lett., 2015, 17, 1349-1352.

5. Ying Xie, Tengfei Chen, Shaomin Fu, Guoqiang Li, Huanfeng Jiang, Wei Zeng*. Chem.Comm., 2015, 51, 9377- 9380.

4. Ying Xie, Tengfei Chen, Shaomin Fu, Xing-Shu Li, Yuanfu Deng, Huanfeng Jiang and Wei Zeng*. Chem. Comm., 2014, 50, 10699-10702.

3. Jiayan Chen, Ling Dang, Qiang Li, Yong Ye, Shaomin Fu, Wei Zeng*. Synlett.,2012, 23, 595- 600.

2. Shujie Zhu, Jia Dong, Shaomin Fu, Huanfeng Jiang, and Wei Zeng*. Org. Lett.,2011, 13, 4914-4917.

1. Xiaoyan Lian, Shaomin Fu, Tongmei Ma, Shunbin Li and Wei Zeng*. Appl. Organometal. Chem.,2011, 25, 443- 447.

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