Sept. 1983 - Mar. 1993: Organic Chemistry and Bio-organic Chemistry BSc, MS, PhD, Department of Chemistry, Sichuan University.
April 1993 - June 1999: Lecturer, Associate Professor, Department of Chemistry, Sichuan University.
April 1998 - Mar. 2001: Research Associate, Department of Chemistry, the University of Hong Kong.
July 1999 - Oct. 2009: Professor, College of Chemistry, Sichuan University.
Nov. 2009 - present: Chang Jiang Chair Professor, College of Chemistry, Sichuan University.
Dec. 2010 - present: Dean and Chang Jiang Chair Professor, College of Chemistry, Sichuan University.
SELECTED AWARDS AND HONORS:
2001: Excellent teacher award by College of Chem, Sichuan University
2003: Outstanding young scientist award by Sichuan Province
2003:New century excellent talent award by Ministry of Education of China
2004: Excellent teacher award by Sichuan University
2006:Scholar Leadership awarded by Sichuan Province
2007: Distinguished Young Scholars Awarded byNational Science Foundation of China
2009:Chang Jiang Chair Professor by Ministry of Education of China
RESEARCH INTERESTS AND EXPERTISE:
1、BiomedicalMaterials Chemistry
2、Methodology of Organic Syntheses
REPRESENTATIVE PUBLICATIONS:
(5). Zhang, Q.-F., Yi, W.-J., Wang, B., Zhang, J.*, Ren, L.-F., Chen, Q.-M., Guo, L.-D.*,Yu, X.-Q.*, Linear polycations by ring-opening polymerization as non-viral gene delivery vectors.Biomaterials,2013,34, 5391-5401.
(4). Huang, Q.-D., Ren, J., Chen, H., Ou, W.-J., Zhang, J.*, Fu, Y., Zhu, W.*,Yu, X.-Q.*, Cyclen-Based Cationic Lipids Containing Carbamate Linkages as Efficient Gene Delivery Vectors with Low Toxicity.ChemPlusChem,2012,77, 584-591.
(3). Huang, Q.-D., Zhong, G.-X., Zhang, Y., Ren, J., Fu, Y., Zhang, J.*, Zhu, W.*,Yu, X.-Q.*, Cyclen-Based Cationic Lipids for Highly Efficient Gene Delivery towards Tumor Cells.PLoS ONE,2011,6, e23134. doi:10.1371/journal.pone.0023134.
(2). Chen, X., Huang, Z., Chen, S.-Y., Li, K.,Yu, X.-Q.*, Pu, L.*, Enantioselective Gel Collapsing: A New Means of Visual Chiral Sensing.J. Am. Chem. Soc.,2010,132, 7297–7299.
(1). Wen, J., Zhang, J., Chen, S.-Y., Li, J.,Yu, X.-Q.*, Iron-Mediated Direct Arylation of Unactivated Arenes.Angew. Chem. Int. Ed.,2008,47, 8897-8900.
SELECTED PUBLICATIONS：
(110).Zhang, Q.-F., Yi, W.-J., Wang, B., Zhang, J.*, Ren, L.-F., Chen, Q.-M., Guo, L.-D.*,Yu, X.-Q.*, Linear polycations by ring-opening polymerization as non-viral gene delivery vectors,Biomaterials,2013,34, 5391-5401.
(109).Chen, W., Tay, J.-H. Ying, J., Sabat, M.,Yu, X.-Q.*, Pu, L.*,A quick access to the spirotricyclic core analogue of mangicol A by a Rh( I )-catalyzed tandem Pauson–Khand/[4+2] cycloaddition,Chem. Commun.,2013,49, 170-172.
(108).Xu, H.-R., Li, K.*, Liu, Q., Wu, T.-M., Wang, M.-Q., Hou, J.-T., Huang, Z., Xie, Y.-M.*,Yu, X.-Q.*, Dianthracene–cyclen conjugate: the ?rst equal-equivalent responding ?uorescent chemosensor for Pb2+in aqueous solution,Analyst,2013,138, 2329–2334.
(107).Wu, M.-Y., He, T., Li, K.*, Wu, M.-B., Huang, Z.,Yu, X.-Q.*, A real-time colorimetric and ratiometric ?uorescent probe for sul?te,Analyst,2013,138, 3018–3025.
(106).Liu, Q., Jiang, Q.-Q., Yi, W.-J., Zhang, J.*, Zhang, X.-C., Wu, M.-B., Zhang, Y.-M., Zhu, W.*,Yu, X.-Q.*,Novel imidazole-functionalized cyclen cationic lipids: Synthesis and application as non-viral gene vectors,Bioorg. Med. Chem.2013,21, 3105–3113.
(105). Li, K., Xu, H.-R., Yu, K.-K., Hou, J.-T.,Yu, X.-Q.*, A coumarin-based chromogenic and ratiometric probe for hydrazine,Anal. Methods,2013,5, 2653-2656.
(104).Chen, W., Tay, J.-H. Ying, J.,Yu,,X.-Q.*, Pu, L.*,Catalytic Asymmetric Enyne Addition to Aldehdyes and Rh(I)-Catalyzed Stereoselective Domino Pauson ? Khand/[4 + 2] Cycloaddition,J. Org. Chem.2013,78, 2256 – 2265.
(103).Zhou, Y.-J., Hu, C.-L., Wang, N.*, Zhang, W.-W.,Yu, X.-Q.*, Puri?cation of porcine pancreatic lipase by aqueous two-phase systems of polyethylene glycol and potassium phosphate,J. Chromatography B,2013,926, 77–82.
(102).Lu, Q.-S., Hou, J.-T., Wang, J., Xu, B.-Y., Zhang, J.*,Yu, X.-Q.*, Multichannel Chromogenic and Chiral Anions Recognition by Imidazolium Functionalized BINOL Derivatives,Chin. J. Chem.2013,31, 641-650.
(103).Zhou, L.-H., Wang, N.*, Zhang, W., Xie, Z.-B.,Yu, X.-Q.*, Catalytical promiscuity of a-amylase: Synthesis of 3-substituted 2H-chromene derivatives via biocatalytic domino oxa-Michael/aldol condensations,J. Mol. Catal. B: Enzym.,2013,91, 37–43.
(101).Tao, F-Y., Wang, C.-G., Ma, K.-Y., Li, D.-L., Tan, L.-L., Zhang, J., Dai, Y.*,Yu, X.-Q.*, A facile synthesis and application of protoporphyrin derivatives on reducing the tobacco specific N-nitroamines levels of smoke,J. Porphyrins Phthalocyanines2013,17, 309–316.
(100).Xun, M.-M., Zhang, X.-C., Zhang, J.*, Jiang, Q.-Q., Yi, W.-J., Zhu, W.*,Yu, X.-Q.*, Low molecular weight PEI-based biodegradable lipopolymers as gene delivery vectors,Org. Biomol. Chem.,2013,11, 1242–1250.
(99). Hou, J.-T., Li. K.*, Yu, K.-K., Wu, M.-Y.,Yu, X.-Q.*, Coumarin–DPA–Cu(II) as a chemosensing ensemble towards histidine determination in urine and serum,Org. Biomol. Chem.,2013,11, 717-720.
(98). Hou, J.-T., Li, K.*, Liu, B.-Y., Liao, Y.-X.,Yu, X.-Q.*, The ?rst ratiometric probe for lysine in water,Tetrahedron,2013,69, 2118-2123.
(97). He, T., Li, K.*, Wu, M.-Y., Wu, M.-B., Wang, N., Pu, L.,Yu, X.-Q.*, Water promoted enantioselective aldol Reaction by proline-cholesterol and -diosgenin based amphiphilic organocatalysts,Tetrahedron,2013,69, 5136-5143.
(96). Xie, Z.-B., Wang, N.*, Jiang, G.-F.,Yu, X.-Q.*, Biocatalytic asymmetric aldol reaction in buffer solution,Tetrahedron Lett.2013,54, 945–948.
(95). Feng, J., Yang, X.-B., Liang, S., Zhang, J.*,Yu, X.-Q.*,An ef?cient oxidative coupling method for synthesis of noveldiastereomeric biaryl diols derived from estrone,Tetrahedron Lett.2013,54, 355–357.
(94). Wang, J., Wang, S., Wang, G., Zhang, J.*,Yu, X.-Q.*, Iron-mediated direct arylation with arylboronic acids through an aryl radical transfer pathway,Chem. Commun.,2012,48, 11769–11771.
(93). Huang, Z., Du, J., Zhang, J.,Yu, X.-Q.*, Pu, L.*, A simple and e?cient ?uorescent sensor for histidine,Chem. Commun.,2012,48, 3412-3414.
(92). Huang, Q.-D., Ren, J., Chen, H., Ou, W.-J., Zhang, J.*, Fu, Y., Zhu, W.*,Yu, X.-Q.*, Cyclen-Based Cationic Lipids Containing Carbamate Linkages as Efficient Gene Delivery Vectors with Low Toxicity,ChemPlusChem,2012,77, 584-591.
(91). Wen, J., Zhang, R.-Y., Chen, S.-Y., Zhang J.*,Yu, X.-Q.*, Direct Arylation of Arene and N-Heteroarenes with Diaryliodonium Salts without the Use of Transition Metal Catalyst,J. Org. Chem.,2012,77, 766-771.
(90). Wang, M.-Q., Li, K.*, Hou, J.-T., Wu, M.-Y., Huang, Z.,Yu, X.-Q.*, BINOL-Based Fluorescent Sensor for Recognition of Cu(II) and Sul?de Anion in Water,J. Org. Chem.,2012,77, 8350?8354.
(89). Chen, W., Tay, J.-H.,Yu, X.-Q.*, Pu, L.*, Diastereoselective [4 + 1] Cycloaddition of Alkenyl Propargyl Acetates with CO Catalyzed by [RhCl(CO)2]2,J. Org. Chem.,2012,77, 6215?6222.
(87). Wu, M.-Y., Li, K*, Hou, J.-T., Huang, Z.,Yu, X.-Q.*, A selective colorimetric and ratiometric ?uorescent probe for hydrogen sul?de,Org. Biomol. Chem.,2012,10, 8342-8347.
(86). Huang, Q.-D., Ren, J., Ou, W.-J., Fu, Y., Cai, M.-Q., Zhang, J.*, Zhu, W.*,Yu, X.-Q.*, Cationic Lipids Containing Cyclen and Ammonium Moieties as Gene Delivery Vectors,Chem. Biol. Drug Des.,2012,79, 879-887.
(85). Li, S., Wang, Y., Wang, S., Zhang, J.*, Wu, S.-F., Wang, B.-L., Zhu, W.*,Yu, X.-Q.*, Biodegradable cyclen-based linear and cross-linked polymers as non-viral gene vectors,Bioorg. Med. Chem.,2012,20, 1380–1387.
(84). Zhang, W.-W., Wang, N.*, Zhou, Y.-J., He, T.,Yu, X.-Q.*, Enhancement of activity and stability of lipase by microemulsion-based organogels (MBGs) Immobilization and application for synthesis of arylethyl acetate,J. Mol. Catal. B: Enzymatic,2012,78, 65–71.
(83). Feng, J., Liang, S., Chen, S.-Y., Zhang, J.*, Fu, S.-S.,Yu, X.-Q.*, A Metal-Free Oxidative Esterification of the Benzyl C-H Bond,Adv. Synth. Catal.,2012,354, 1287-1292.
(82). Huang, Z., Du, J., Zhang, J.,Yu, X.-Q.*, Pu, L.*, Highly selective ?uorescent recognition of Zn2+in water by terpyridine–CuCl2,Anal. Methods,2012,4, 1909-1912.
(81). Xie, Z.-B., Wang, N.*, Wu, M.-Y., He, T., Le, Z.-G.,Yu, X.-Q.*, Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method,Beilstein J. Org. Chem.,2012,8, 534–538.
(80). Wen, J., Fu, Y., Zhang, R.-Y., Zhang, J.*, Chen, S.-Y.,Yu, X.-Q.*, A simple and ef?cient synthesis of pyrazoles in water,Tetrahedron,2011,67, 9618-9621.
(79). Zhang, Q.-F., Yang, W.-H., Yi, W.-J., Zhang, J.*, Ren, J., Luo, T.-Y., Zhu, W.*,Yu, X.-Q.*, TACN-containing cationic lipids with ester bond: Preparation and application in gene deliveryBioorg. Med. Chem. Lett.,2011,21, 7045–7049.
(78). Wang, J., Hou, J.-T., Wen, J., Zhang, J.*,Yu, X.-Q.*, Iron-catalyzed direct amination of azoles using formamides or amines as nitrogen sources in air,Chem. Commun.,2011,47, 3652-3654.
(77). Wang,M.-Q., Liu,J.-L., Wang,J.-Y., Zhang,D.-W., Zhang,J., Streckenbach,F., Tang,Z.*, Lin,H.-H.*, Liu,Y., Zhao,Y.-F.,Yu,X.-Q.*,Site-selective DNA Hydrolysis Induced by a Metal-free Peptide Nucleic Acid-Cyclen Conjugate,Chem. Commun., 2011,47, 11059-11061.
(76). Liu, J.-L., Ma, Q.-P., Huang, Q.-D., Yang, W.-H.,Zhang, J.*,Wang, J.-Y., Zhu, W.,Yu, X.-Q.*,Cationic lipids containing protonated cyclen and different hydrophobic groups linked by uracil-PNA monomer: Synthesis and application for gene delivery,Eur. J. Med. Chem.,2011,46, 4133-4141.
(75). Huang, Q.-D., Zhong, G.-X., Zhang, Y., Ren, J., Fu, Y., Zhang, J.*, Zhu, W.*,Yu, X.-Q.*, Cyclen-Based Cationic Lipids for Highly Efficient Gene Delivery towards Tumor Cells,PLoS ONE,2011,6, e23134. doi:10.1371/journal.pone.0023134.
(74). Huang, Q.-D., Ou, W.-J., Chen, H., Feng, Z.-H., Wang, J.-Y., Zhang, J.*, Zhu, W.*,Yu, X.-Q.*, Novel cationic lipids possessing protonated cyclen and imidazolium salt for gene delivery,Eur. J. Pharm. Biopharm.,2011,78, 326–335.
(73). Wang, H.-Y., Zhou, Y.-J., Wang, Z., Wang, N.*, Li, K.,Yu, X.-Q.*, Enzyme-Catalyzed Synthesis of a Novel Thermosensitive Polyester with Pendant Ketoprofen,Macromol. Biosci.,2011,11, 595–599.
(72). Wu, M.-Y., Li, K.*, Wang, N., He, T.,Yu, X.-Q.*, A Novel Catalyst-Free Tandem Reaction for the Synthesis of 5-Hydroxy-1,5-dihydro-2H-pyrrol-2-ones in Water Medium,Synthesis,2011,12, 1831–1839.
(71). Li, S., Wang, Y., Zhang, J.*, Yang, W.-H., Dai, Z.-H., Zhu, W.*,Yu, X.-Q.*, Biodegradable cross-linked poly(amino alcohol esters) based on LMW PEI for gene delivery,Mol. BioSyst.,2011,7, 1254-1262.
(70). Yi, W.-J., Feng, Z.-H., Zhang, Q.-F., Zhang, J.*, Li, L.-D., Zhu, W.*,Yu, X.-Q.*, Diol glycidyl ether-bridged cyclens: preparation and their applications in gene delivery,Org. Biomol. Chem.,2011,9, 2413-2421.
(69). Wang, M.-Q., Zhang, J., Zhang, Y., Zhang, D.-W., Liu, Q., Liu, J.-L., Lin, H.-H.*,Yu, X.-Q.*,Metal-free Cleavage Efficiency toward DNA by a Novel PNA Analog-bridged Macrocyclic Polyamine,Bioorg. Med. Chem. Lett.,2011,21, 5866-5869.
(68). Ye, Y.-H., Zhang, J., Wang, G., Chen, S.-Y.*,Yu, X.-Q.*, Cobalt-catalyzed benzylic CeH amination via dehydrogenative-coupling reaction,Tetrahedron,2011,67, 4649-4654.
(67). Hou, J.-T., Zhang, Q.-F., Xu, B.-Y., Lu, Q.-S., Liu, Q., Zhang, J.,Yu, X.-Q.*, A novel BINOL-based cyclophane via click chemistry: synthesis and its applications for sensing silver ions,Tetrahedron Lett.,2011,52, 4927–4930.
(66). Du, X., Wang, Q.*, He, X., Peng, R.-G., Zhang, X.,Yu, X.-Q.*, Highly enantioselective addition of linear alkyl alkynes to aromatic aldehydes,Tetrahedron: Asymmetry,2011,22, 1142–1146.
(65). Wu, M.-Y., Li, K.*, He, T., Feng, X.-W., Wang, N., Wang, X.-Y.,Yu, X.-Q.*, A novel enzymatic tandem process: utilization of biocatalytic promiscuity for high stereoselective synthesis of 5-hydroxyimino-4,5-dihydrofurans,Tetrahedron,2011,67, 2681-2688.
(64). Wu, M.-Y., Wang, M.-Q., Li, K.*, Feng, X.-W., He, T., Wang, N.,Yu, X.-Q.*, An ef?cient, transition-metal-free process for the synthesis of substituted dihydrofurans via a Michael/cyclization tandem reaction,Tetrahedron Lett.2011,52, 679–683.
(63). Huang, Z., Chen, X., Zhang, J.,Yu, X.-Q.*, Pu, L.*, Connecting BINOL and Terpyridine: The Electronic Effects of the Linkage,Tetrahedron Lett.,2011,52, 5497–5500.
(62). Zhang, Y., Wang, M.-Q., Zhang, J., Zhang, D.-W., Lin, H.-H.*,Yu, X.-Q.*, Synthesis, DNA Binding, and Cleavage Studies of Novel PNA Binding Cyclen Complexes,Chem. Biodivers.,2011,8, 827-840.
(61). Zhang, Y., Huang, Y., Zhang, J., Zhang, D.-W., Liu, J.-L., Liu, Q., Lin, H.-H.*,Yu, X.-Q.*, Synthesis, DNA binding and cleavage studies of the copper(II) complexes of PNA-cyclen conjugates, Sci. China Chem.,2011,54(1), 129-136.
(60). Wang, H.-Y., Zhang, W.-W., Wang, N.,* Li, C., Li, K.,Yu, X.-Q.*, Biocatalytic Synthesis and in Vitro Release of Biodegradable Linear Polyesters with Pendant KetoprofenBiomacromolecules,2010,11, 3290–3293.
(59). Liu, Q., Zhang, J., Wang, M.-Q., Zhang, D.-W., Lu, Q.-S., Huang, Y., Lin, H.-H.*,Yu, X.-Q.*, Synthesis, DNA binding and cleavage activity of macrocyclic polyamines bearing mono- or bis-acridine moieties,Eur. J. Med. Chem.,2010,45, 5302-5308.
(58). Li, C., Zhou, Y.-J., Wang N.*, Feng, X.-W., Li, K.,Yu, X.-Q.*, Promiscuous protease-catalyzed aldol reactions: A facile biocatalytic protocol for carbon–carbon bond formation in aqueous media,J.Biotech.,2010,150,539–545.
(57). Qin, J., Meng, X.-W., Li, B.-J., Ha, W.,Yu, X.-Q.*, Zhang, S.*, Self-assembly of b-cyclodextrin and pluronic into hollow nanospheres in aqueous solution,J. Colloid Interface Sci.,2010,350, 447–452.
(56). He, T., Li, K.*, Wu, M.-Y., Feng, X.-W., Wang, N., Wang, H.-Y., Li, C.,Yu, X.-Q.*,Utilization of biocatalytic promiscuity for direct Mannich reaction,J.Mol.Catal.B: Enzym.,2010,67,189–194.
(55). Wang, L., Li, C., Wang, N.*, Li, K., Chen, X.,Yu, X.-Q.*, Enzyme-mediated domino synthesis of 2-alkylbenzimidazoles in solvent-free system: A green route to heterocyclic compound,J.Mol.Catal.B: Enzym.,2010,67,16–20.
(54). Turlington, M., Yue, Y.,Yu, X.-Q.*, Pu, L.*, Catalytic Asymmetric Synthesis of Chiral Propargylic Alcohols for the Intramolecular Pauson-Khand Cycloaddition,J. Org. Chem.,2010,75, 6941–6952.
(53). Feng, X.-W., Wang, J., Zhang, J., Yang, J., Wang, N.,Yu, X.-Q.*, Copper-Catalyzed Nitrogen Loss of Sulfonylhydrazones: A Reductive Strategy for the Synthesis of Sulfones from Carbonyl Compounds,Org. Lett.,2010,12, 4408-4411.
(52). Lu, Q.-S., Zhang, J., Jiang, L., Hou, J.-T.,Yu, X.-Q.*, Highly selective ratiometric estimation of ?uoride ion based on a BINOL imidazolium cyclophane with dual-channel,Tetrahedron Lett.,2010,51, 4395–4399.
(51). Chen, X., Huang, Z., Chen, S.-Y., Li, K.,Yu, X.-Q.*, Pu, L.*, Enantioselective Gel Collapsing: A New Means of Visual Chiral Sensing,J. Am. Chem. Soc.,2010,132, 7297–7299.
(50). Wen, J., Qin, S., Ma, L.-F., Dong, L., Zhang, J., Liu, S.-S., Duan, Y.-S., Chen, S.-Y., Hu, C.-W.*,Yu, X.-Q.*, Iron-Mediated Direct Suzuki-Miyaura Reaction: A New Method for the ortho-Arylation of Pyrrole and Pyridine,Org. Lett.,2010,12, 2694-2697.
(49). Xiang, Y.-Z.,Feng, Z.-H.,Zhang, J.*,Liao, Y.-L.,Yu, C.-J.,Yi, W.-J.,Zhu, W.*,Yu, X.-Q.*,Linear cyclen-based polyamine as a novel and efficient reagent in gene delivery,Org. Biomol. Chem.,2010,8,640–647.
(48). Chen, X., Chen, W., Wang, L.,Yu, X.-Q.*, Huang, D.-S., Pu, L.*,Synthesis of aC1 symmetric BINOL–terpyridine ligand and highly enantioselective methyl propiolate addition to aromatic aldehydes,Tetrahedron,2010,66, 1990–1993.
(47). Chen, X., Liu, Q., Sun, H.-B.,Yu, X.-Q.*, Pu, L.*, A BINOL–terpyridine-based multi-task catalyst for a sequential oxidation and asymmetric alkylation of alcohols,Tetrahedron Lett.,2010,51, 2345–2347.
(46). Huang, Y., Liu, J.-L., Zhang, J., Liu, Q., Hou, J.-T., Zhang, Y., Zhang, D.-W., Lu, Q.-S., Chen, S.-Y., Lin, H.-H.,Yu, X.-Q.*, Interaction of bis-aryl functionalized molecules with nucleosides and nucleic acids,Sci. China Chem.,2010,53, 103–112.
(45). Zhou, L.-H.,Yu, X.-Q.*, Pu, L.*,Reactivity of a propiolate dimer with nucleophiles and an efficient synthesisof dimethyl a-aminoadipate,Tetrahedron Lett.,2010,51, 425–427.
(44). Zhou, L.-H.,Yu, X.-Q.*, Pu, L.*,Na-promoted aerobic oxidation of alcohols to ketones,Tetrahedron Lett.,2010,51, 475–477.
(43). Meng, X.-W.,Qin, J.,Liu, Y.,Fan, M.-M.,Li, B.-J.*, Zhang, S.*,Yu, X.-Q., Degradable hollow spheres based on self-assembly inclusion,Chem. Commun.,2010,46, 643–645.
(42). Zhang, J., Meng, X.-G., Zeng, X.-C.,Yu, X.-Q.*, Metallomicellar supramolecular systems and their applications in catalytic reactions,Coord. Chem. Rev.,2009,253, 2166–2177.
(41). Yue, Y.,Yu, X.-Q.*, Pu, L.*, Base-Catalyzed Highly Stereoselective Conversion ofg-Hydroxy-a,b-acetylenic Esters tog-Acetoxy Dienoates,Chem. Eur. J.,2009,15, 5104-5107.
(40). Lu, Q.-S., Dong, L., Zhang, J., Li, J., Jiang, L., Huang, Y., Qin, S., Hu, C.-W.,Yu, X.-Q.*, Imidazolium-Functionalized BINOL as a Multifunctional Receptor for Chromogenic and Chiral Anion Recognition,Org. Lett.,2009,11, 669-672.
(39). Li, K., He, T., Li, C., Feng, X.-W., Wang, N.,Yu, X.-Q.*, Lipase-catalysed direct Mannich reaction in water: utilization of biocatalytic promiscuity to C-C bond formation in a “one-pot” synthesis,Green Chem.,2009,11, 777-779.
(38). Zhou, L.-H.,Yu, X.-Q.*, Pu, L.*, Reactivity of γ-Hydroxy-α,β-acetylenic Esters with Amines: Facile Synthesis of the Optically Active 4-Amino-2(5H)-furanones,J. Org. Chem.,2009,74, 2013–2017.
(37). Huang, Y., Zhang, Y., Zhang, J., Zhang, D.-W., Lu, Q.-S., Liu, J.-L., Chen, S.-Y., Lin, H.-H.,Yu, X.-Q.*,Synthesis, DNA binding and photocleavage study of novel anthracene-appended macrocyclic polyamines,Org. Biomol. Chem.,2009,7, 2278-2285.
(36). Wang, H.-Y., Li, C., Wang, N.*, Li, K., Feng, X.-W., He, T., Yu, X.-Q.*, Two-step enzymatic selective synthesis of water-soluble ketoprofen -saccharide conjugates in organic media,Bioorg. Med. Chem.,2009,17,1905-1910.
(35). Li, K., Zhou, L.-H., Zhang, J., Chen, S.-Y., Zhang, Z.-W., Zhang, J.-J., Lin, H.-H.,Yu, X.-Q.*,“Self-activating” Chemical Nuclease: Ferrocenyl Cyclen Cu(II) Complexes Act as Efficient DNA Cleavage Reagents in the Absence of Reductant,Eur. J. Med. Chem.,2009,44, 1768-1772.
(34). Xiang, Y.-Z., Liao, Y.-L., Zhang, J.*, Zhang, D.-W., Chen, S.-Y., Lu, Q.-S., Zhang, Y., Lin, H.-H,*,Yu, X.-Q.*,Linear disulfide-containing low polymer as efficient DNA cleavage reagent,Bioorg. Med. Chem. Lett.,2009,19, 3458–3460.
(33). Li, J., Zhang, J., Lu, Q.-S., Yue, Y., Huang, Y., Zhang, D.-W., Lin, H.-H., Chen, S.-Y.,Yu, X.-Q.*,Hydrolytic cleavage of DNA by urea-bridged macrocyclic polyamines,Eur. J. Med. Chem.,2009,44, 5090–5093.
(32). Chen, S.-Y., Zhang, J., Li, Y.-H., Wen, J., Bian, S.-Q.,Yu, X.-Q.*, Cobalt-catalyzed homo-coupling of aryl and alkenyl bromide using atmospheric oxygen as oxidant,Tetrahedron Lett.,2009,50, 6795–6797.
(31). Feng, X.-W., Li, C., Wang, N.*, Li, K., Zhang, W.-W., Wang, Z.,Yu, X.-Q.*, Lipase-catalysed decarboxylative aldol reaction and decarboxylative Knoevenagel reaction,Green Chem.,2009,11, 1933-1936.
(30). Yue, Y, Turlington, M.,Yu, X.-Q.*, Pu, L.*, 3,3’-Anisyl-Substituted BINOL, H4BINOL, and H8BINOL Ligands: Asymmetric Synthesis of Diverse Propargylic Alcohols and Their Ring-Closing Metathesis to Chiral Cycloalkenes,J. Org. Chem.,2009,74, 8681-8689.
(29). Wen, J., Zhang, J., Chen, S.-Y., Li, J.,Yu, X.-Q.*, Iron-Mediated Direct Arylation of Unactivated Arenes,Angew. Chem. Int. Ed.,2008,47, 8897-8900.
(28). Zheng, Z.-G., Wen, J., Wang, N., Wu, B.,Yu, X.-Q.*,N-Arylation of amines, amides, imides and sulfonamides with arylboroxines catalyzed by simple copper salt/EtOH system,Beilstein J. Org. Chem.,2008,4, No. 40. doi:10.3762/bjoc.4.40
(27). Li, C.,Feng,X.-W., Wang,N., Zhou,Y.-J.,Yu,X.-Q.*, Biocatalytic promiscuity: the first lipase-catalysed asymmetric aldol reaction,Green Chem.,2008,10, 616-618.
(26). Yang, X.-B., Feng, J., Zhang, J., Wang, N., Wang, L., Liu, J.-L.,Yu, X.-Q*, Highly Enantioselective Hetero-Diels?-Alder Reaction of trans-1-Methoxy-2-methyl-3-trimethylsiloxybuta-1,3-diene with Aromatic and Aliphatic Aldehydes Catalyzed by 3-Substituted BINOL-Titanium Complex,Org. Lett.,2008,10, 1299-1302.
(25). Huang, Y.,Lu, Q.-S.,Zhang, J.,Zhang, Z.-W.,Zhang, Y.,Chen, S.-Y.,Li, K.,Tan, X.-Y.,Lin, H.-H.,Yu, X.-Q.*,DNA cleavage by novel copper (II) complex and the role of ?-cyclodextrin in promoting cleavage,Bioorg. Med. Chem.,2008,16, 1103-1110.
(24). Yang, X.-B.,Feng, J.,Zhang, J.,Zhang, Z.-W.,Lin, H.-H.,Zhou, L.-H.,Yu, X.-Q.*,Synthesis, DNA binding and cleavage activities of the copper(II) complexes of estrogen-macrocyclic polyamine conjugates,Bioorg. Med. Chem.,2008,16, 3871-3877.
(23). Li, C., Wang, H.-Y. Wang, N.,*Fang, Y.-G., Chen, X.,Yu, X.-Q.*,Highly regioselective enzymatic synthesis of polymerizable derivatives of methyl shikimate,Bioorg. Med. Chem. Lett.,2007,17, 6687-6690.
(22). He, L., Yu, J., Zhang, J.,Yu, X.-Q.*, ?-Amidation of cyclic ethers catalyzed by simple copper salts and a mild and efficient preparation method for ?,?-aminoalcohols,Org. Lett.,2007,9, 2277-2280.
(21). Wang, Q., Chen, X., Tao, L., Wang, L., Xiao, D.,Yu, X.-Q.*, Pu, L.*, Enantioselective Fluorescent Recognition of Amino Alcohols by a Chiral Tetrahydroxyl 1,1’-Binaphthyl Compound,J. Org. Chem.,2007, 72,97-101.
(20). Fang, Y.-G., Zhang, J., Chen, S.-Y., Jiang, N.,Lin, H.-H., Zhang, Y.,Yu, X.-Q.*, Chiral multinuclear macrocyclic polyamine complexes: Synthesis,characterization and their interaction with plasmid DNA,Bioorg. Med. Chem.,2007,15,696-701.
(19). Wang, Q., Chen, S.-Y.,Yu, X.-Q.*, Pu, L.*, 1,1’-Binaphthyl ligands with bulky 3,3’-tertiaryalkyl substitutes for the asymmetric alkyne addition to aromatic aldehydes,Tetrahedron,2007,63,4422-4428.
(18).Zhao, Y.-C., Zhang, J., Huang, Y., Wang, G.-Q.,Yu, X,-Q.*,DNA cleavage promoted by 2, 9-dimethyl-4, 7-diazadecane-2, 9-dithiol (DMDD) derivatives,Bioorg. Med. Chem. Lett.,2007,17, 2745-2748.
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